Javier Camacho Selected Research

Potassium Channels (Potassium Channel)

12/2017	Astemizole inhibits cell proliferation in human prostate tumorigenic cells expressing ether à-go-go-1 potassium channels.
1/2017	The combination astemizole-gefitinib as a potential therapy for human lung cancer.
8/2015	Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.
8/2015	Astemizole-based anticancer therapy for hepatocellular carcinoma (HCC), and Eag1 channels as potential early-stage markers of HCC.
1/2015	Differential regulation of human Eag1 channel expression by serum and epidermal growth factor in lung and breast cancer cells.
10/2014	In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors.
6/2014	Antiproliferative and proapoptotic effects of astemizole on cervical cancer cells.
1/2013	Expression of Eag1 K+ channel and ErbBs in human pituitary adenomas: cytoskeleton arrangement patterns in cultured cells.
1/2012	Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy.
12/2011	Eag1 potassium channels as markers of cervical dysplasia.

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Javier Camacho Research Topics

Disease

35	Neoplasms (Cancer) 01/2022 - 10/2004
8	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2018 - 10/2004
8	Breast Neoplasms (Breast Cancer) 01/2015 - 02/2007
6	Fibrosis (Cirrhosis) 06/2019 - 08/2015
6	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2012
5	Carcinogenesis 07/2017 - 02/2010
4	Inflammation (Inflammations) 01/2022 - 01/2016
4	Retinoblastoma (Glioblastoma, Retinal) 08/2020 - 07/2017
4	Liver Cirrhosis (Hepatic Cirrhosis) 06/2019 - 12/2017
4	Lung Neoplasms (Lung Cancer) 01/2017 - 04/2011
2	Uterine Cervical Dysplasia 05/2018 - 12/2011
2	Prostatic Neoplasms (Prostate Cancer) 12/2017 - 03/2007
2	Body Weight (Weight, Body) 12/2017 - 10/2014
1	Adenocarcinoma 07/2022
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Hepatic Encephalopathy 12/2018
1	Carcinoma (Carcinomatosis) 05/2018
1	Ovarian Neoplasms (Ovarian Cancer) 05/2018
1	Necrosis 01/2018
1	Cholestasis 01/2018
1	Leukemia 01/2017
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2016
1	Liver Diseases (Liver Disease) 01/2016

Drug/Important Bio-Agent (IBA)

17	Potassium Channels (Potassium Channel)IBA 12/2017 - 02/2006
12	Ether (Diethyl Ether)IBA 01/2020 - 02/2006
11	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2004
11	Tumor Biomarkers (Tumor Markers)IBA 01/2020 - 10/2004
10	Ion Channels (Ion Channel)IBA 01/2022 - 02/2007
9	AstemizoleIBA 01/2020 - 03/2011
7	Pharmaceutical PreparationsIBA 01/2022 - 03/2011
7	Messenger RNA (mRNA)IBA 01/2020 - 10/2004
5	Calcitriol (Calcijex)FDA LinkGeneric 10/2014 - 02/2010
4	Histamine Receptors (Histamine Receptor)IBA 01/2020 - 03/2007
4	Antineoplastic Agents (Antineoplastics)IBA 10/2014 - 02/2010
4	Ether-A-Go-Go Potassium ChannelsIBA 03/2011 - 10/2004
3	Estrogens (Estrogen)FDA Link 01/2020 - 04/2009
3	MicroRNAs (MicroRNA)IBA 01/2020 - 12/2012
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020 - 01/2017
3	Hormones (Hormone)IBA 01/2020 - 02/2010
3	LipopolysaccharidesIBA 06/2019 - 08/2005
3	AntioxidantsIBA 05/2019 - 05/2016
3	Indicators and Reagents (Reagents)IBA 01/2018 - 04/2009
3	Calcitriol Receptors (Calcitriol Receptor)IBA 10/2014 - 07/2010
3	Estrogen ReceptorsIBA 03/2014 - 05/2011
2	AndrogensIBA 01/2020 - 03/2007
2	Histamine Antagonists (Antihistamines)IBA 01/2020 - 01/2017
2	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 01/2020 - 01/2012
2	Metalloproteases (Metalloproteinases)IBA 06/2019 - 12/2017
2	steviosideIBA 06/2019 - 05/2019
2	Ethanol (Ethyl Alcohol)IBA 06/2019 - 05/2019
2	Thioacetamide (Thioacetamid)IBA 06/2019 - 12/2018
2	Transforming Growth Factor beta (TGF-beta)IBA 12/2018 - 04/2011
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2018 - 01/2009
2	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2018 - 08/2015
2	CollagenIBA 01/2018 - 06/2007
2	Epidermal Growth Factor (EGF)IBA 01/2015 - 01/2013
2	Estrogen Receptor Modulators (Antiestrogen)IBA 03/2014 - 04/2009
2	Tamoxifen FDA LinkGeneric 12/2012 - 05/2011
2	Histamine (Histamine Dihydrochloride)FDA Link 03/2011 - 03/2007
1	Ferritins (Ferritin)IBA 01/2022
1	C-Reactive ProteinIBA 01/2022
1	Phosphotransferases (Kinase)IBA 08/2020
1	Vitamin D FDA LinkGeneric 01/2020
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2020
1	DiterpenesIBA 06/2019
1	Carbon Tetrachloride (Tetrachloromethane)IBA 05/2019
1	CarbonIBA 12/2018
1	Dopamine (Intropin)FDA LinkGeneric 12/2018
1	TeaIBA 12/2018
1	Adenosine Triphosphate (ATP)IBA 05/2018
1	Glyburide (Glibenclamide)FDA LinkGeneric 05/2018
1	Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA 05/2018
1	KATP ChannelsIBA 05/2018
1	PotassiumIBA 05/2018
1	iberiotoxinIBA 05/2018
1	CytokinesIBA 01/2018
1	QuercetinIBA 12/2017
1	FlavonoidsIBA 12/2017
1	Gefitinib (Iressa)FDA Link 01/2017
1	1,1-diphenyl-2-picrylhydrazylIBA 05/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	InterleukinsIBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2016
1	Mitochondrial DNA (mtDNA)IBA 01/2016
1	OligonucleotidesIBA 01/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016
1	Cell Adhesion MoleculesIBA 01/2016
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2016
1	CalciumIBA 01/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015
1	Oxygen (Dioxygen)IBA 01/2015
1	U 0126 (UO 126)IBA 01/2015
1	ErbB Receptors (EGF Receptor)IBA 01/2013

Therapy/Procedure

17	Therapeutics 01/2022 - 02/2006
2	Drug Therapy (Chemotherapy) 01/2022 - 12/2012
1	Precision Medicine 07/2022
1	Immunomodulation 12/2017
1	Lasers (Laser) 08/2015
1	Intraperitoneal Injections 10/2014